Active ingredient
Ceramide
INCICeramide NP
Last reviewed by BIOSAR Scientific Team, PharmD, Cosmetic Chemistry, Pharmacy practice on .
Ceramides are skin-identical lipids that make up roughly half of the stratum corneum's intercellular matrix, used in skincare to restore a compromised moisture barrier. Topical ceramides (typically NP, AP, and EOP isoforms) supplement the lamellar structure that holds water inside the skin. Pairs broadly with most actives. No major conflicts.
Considered safe during pregnancy and breastfeeding.
Topical ceramides are considered safe during pregnancy and lactation per Mother to Baby and Trivedi et al. (2017). Ceramides are endogenous skin lipids; topical supplementation does not raise systemic exposure concerns.
What Ceramide does
Skin-identical lipid. Rebuilds the barrier between corneocytes and restores comfort to dry, dehydrated skin.
What the research says
- −25%Water loss about 25% lower two hours after one useOne application of a cream with ceramides, cholesterol, fatty acids and other moisturisers lowered water loss from healthy forearm skin by about 25% at 2 hours and 22% up to 24 hours, against baseline (n=10). A pilot by the cream's maker.Read the study →Clin Cosmet Investig Dermatol 2018 (Spada, Barnes, Greive)
Where it helps
Concerns Ceramide addresses
Aging
The first time you notice it is rarely a wrinkle. It is a quality of light — the way your skin catches it differently in a morning mirror,…
Explore the concernDryness
Dryness is a barrier dysfunction in which skin loses water faster than it can retain or replenish it, presenting as flaking, tightness,…
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If you have sensitive skin, you have probably been told it is in your head — by a product that says "gentle" on the label, by a friend…
Explore the concernSun Damage
Sun damage is the cumulative photoaging caused by ultraviolet radiation, presenting as solar lentigines, irregular pigmentation, fine…
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