Morning routine
Not recommended in the morning; use the Serenity Age Day Cream SPF30+ instead.


Serenity Age Night Cream is BIOSAR's overnight anti-age routine for mature skin. Bakuchiol delivers gentle renewal as a Retinol-compatible alternative; Resveratrol supports antioxidant defense; Peptides reinforce firmness and contour; Hyaluronic Acid restores plumped hydration. Use it every night as the last step of the routine for visibly smoother, more rested skin by morning. The richer texture absorbs without transfer onto pillowcases. Bakuchiol-led formulation is considered safe during pregnancy and breastfeeding under healthcare-provider guidance. Pairs with the Serenity Age Day Cream SPF30+ as a complete day-and-night system.
Wake to visibly renewed, firmer-looking skin. As you sleep, Resveratrol and Ceramide defend and rebuild while Bakuchiol and Peptides smooth fine lines and support firmness with Centella Asiatica calm — a pregnancy-friendly retinol alternative that reveals smoother skin in as little as 4 to 6 weeks.
Proven Benefits
Bakuchiol delivers gentle overnight renewal for firmer-looking mature skin.
Hyaluronic Acid restores plumped hydration while you sleep.
Resveratrol supports antioxidant defense for smoother, more rested skin.
How the actives work together
Night is when Bakuchiol takes the lead, encouraging gentle renewal while you sleep, and it never works alone. Ceramide and Centella Asiatica move with it to keep the skin barrier calm and cushioned, so that renewal feels comfortable rather than demanding. Resveratrol and the Peptide round out the formula, leaving skin rested, supple and quietly restored by morning.
Ingredient Research
In a 12-week trial, a resveratrol antioxidant night serum raised periorbital dermal thickness by 18.9% on ultrasound, with visible gains in firmness, elasticity and fine lines over baseline.
J Drugs Dermatol 2014 (Farris) — View research →A network meta-analysis of five topical Centella asiatica trials in women found it visibly softened wrinkles and markedly raised skin hydration, echoing the calm, cushioned feel of a well-supported barrier.
Kongkaew C, et al. Efficacy and Safety of Centella Asiatica (L.) Urb. on Wrinkles: A Systematic Review and Network Meta-Analysis. J Cosmet Sci. 2020;71(6):439-454. — View research →Transparency
Application Guide
Not recommended in the morning; use the Serenity Age Day Cream SPF30+ instead.
Apply to clean skin as the last step. Massage until absorbed.
Realistic Expectations
Skin looks more hydrated and feels smoother as renewal begins and moisture rebuilds.
The look of fine lines and uneven texture visibly softens, and tone looks brighter.
Complete Care
Complete the routine
Bakuchiol delivers complementary benefits on fine lines and tone with significantly better tolerance. It is photostable, pregnancy-safe, and suitable for reactive skin that does not tolerate Retinol.
Last reviewed by BIOSAR Scientific Team, PharmD, Cosmetic Chemistry, Pharmacy practice on .
Overnight renewal — a pregnancy-friendly retinol alternative.
Ceramide and Centella reinforce the barrier through the night.
A cream built on Ceramide NP plus barrier lipids in skin-matching ratio cut transepidermal water loss by about 25% versus baseline within two hours, and held that seal for a full 24 hours. Dry, depleted skin stays hydrated and calm.
Clin Cosmet Investig Dermatol 2018 (Spada, Barnes, Greive) — View research →Results from published peer-reviewed studies on individual active ingredients. Individual product results may vary.
Resveratrol
A polyphenol antioxidant from grape skin. It helps neutralize the free radicals behind dullness and environmental stress, so overnight skin looks defended, revived and more even by morning.
Centella Asiatica Extract
Botanical compound widely known in pharmacy copy as Cica. Calms the look of sensitivity and supports barrier comfort.
Ceramide NP
Skin-identical lipid. Rebuilds the barrier between corneocytes and restores comfort to dry, dehydrated skin.
Bakuchiol
Plant-derived compound positioned as a gentler alternative to Retinol. Used in night care for sensitive or pregnancy-aware routines.
Palmitoyl Tripeptide-1
Short chains of amino acids that act as messengers in the skin. In anti-aging formulas they support the signals behind firmness and elasticity, softening the look of fine lines for smoother, more resilient skin.
Visibly firmer, more lifted and more radiant skin — age, beautifully managed.
Individual results vary based on skin condition and routine consistency.