Morning routine
Apply a few drops to clean skin before moisturizer and sunscreen.


Serenvit Cica Serum is BIOSAR's calming serum for visibly reactive skin. Centella Asiatica calms surface redness; Panthenol supports overnight repair of the look of irritation; Squalane reinforces the barrier without clogging the surface. Use it morning and night during sensitivity flares, post-active recovery, or whenever the skin feels reactive to climate or product. The texture is fluid and layers cleanly under any moisturizer. Tolerance-tested under dermatological supervision. Pairs with any Sensimed cream or the Serenvit Hyaluronic Acid Serum.
Stressed, reactive skin finds real, lasting calm. Centella Asiatica and Panthenol soothe and rebuild a compromised-looking barrier while Squalane, Jojoba, Macadamia, Chamomile and Calendula replenish and comfort, and Caffeine and Vitamin E refresh, all on a rich Aloe Vera base. Redness settles, skin feels cushioned, resilient and deeply comforted.
Proven Benefits
Centella Asiatica calms the look of surface redness.
Panthenol supports overnight repair of the look of irritation.
Squalane reinforces the barrier without clogging reactive skin.
Calendula and Aloe Vera support post-active and flare recovery.
How the actives work together
Centella Asiatica and Panthenol lead a deeply soothing formula built for skin that feels reactive and overworked. A blend of Squalane, Jojoba and Macadamia oils restores softness, while Chamomile, Calendula and Vitamin E settle the look of redness. Caffeine adds a fresh, awakening note, and the Aloe Vera base carries it all so this becomes one comforting step that leaves skin feeling reset.
Ingredient Research
A network meta-analysis of five topical Centella asiatica trials in women found it visibly softened wrinkles and markedly raised skin hydration, echoing the calm, cushioned feel of a well-supported barrier.
Kongkaew C, et al. Efficacy and Safety of Centella Asiatica (L.) Urb. on Wrinkles: A Systematic Review and Network Meta-Analysis. J Cosmet Sci. 2020;71(6):439-454. — View research →In a 3-month trial, 96% of young participants using a panthenol-containing emollient stayed flare-free, versus 77% on reference care. Provitamin B5 keeps sensitive, barrier-stressed skin soothed and steady day after day.
J Dermatolog Treat 2017 — View research →In a controlled trial, a squalane-and-shea moisturizer raised corneometer-measured skin hydration by 83.6% over two weeks. Squalane slots into the skin's own lipid layer to lock in moisture and restore a soft, comfortable barrier.
Dermatology Research and Practice 2024 — View research →Results from published peer-reviewed studies on individual active ingredients. Individual product results may vary.
Transparency
Centella Asiatica Extract
Botanical compound widely known in pharmacy copy as Cica. Calms the look of sensitivity and supports barrier comfort.
Panthenol (Provitamin B5)
Provitamin B5 that supports the skin's repair and hydration signals. Widely used in sensitive, post-procedure, and daily-care formulas.
Squalane
Skin-mimicking lipid derived from plant sources. Delivers barrier support and a non-greasy finish. Pairs well with Retinol to improve tolerability.
Calendula Officinalis Flower Oil (and separately Calendula Officinalis Flower Extract)
Botanical with soothing properties, traditionally used on reactive skin. Delivered as oil and extract for complementary comfort and barrier support.
Aloe Barbadensis Leaf Juice
Botanical humectant used as a comforting base across serums, baby care, and cleansers. High concentrations deliver noticeable cooling and hydration.
Caffeine
Stimulant that supports local microcirculation where it is applied. In body and eye-area formulas it helps de-puff and firm the look of skin, for a smoother, more toned and visibly refreshed appearance.
Tocopherol
It neutralizes free radicals at the lipid layer, helping limit oxidative damage to formula and skin surface.
Chamomilla Recutita Flower Extract
Botanical extract that calms the appearance of irritation. Suitable for sensitive and baby skin routines.
Simmondsia Chinensis (Jojoba) Seed Oil
Its sebum-like esters condition the surface and help balance the look and feel of oily skin.
Macadamia Integrifolia Seed Oil
Oleic-rich lipids mirror skin's own emollients, spreading into a smooth conditioning layer that softens roughness.
Application Guide
Apply a few drops to clean skin before moisturizer and sunscreen.
Repeat the morning step in the evening routine.
Realistic Expectations
Skin drinks in the serum and feels comfortable, hydrated and cared for.
The targeted concern — hydration, tone, texture or firmness — starts to visibly improve.
The serum's focused benefit reaches its peak with consistent daily use.
Individual results vary based on skin condition and routine consistency.
Complete the routine
Serenvit serums work harder on a hydrated canvas. Follow every serum with Hydraderm as your moisturizer step to seal each active in.
ExploreActives brighten and renew — SPF guards the result. Finish every morning routine with Sunprotex to keep your progress visible.
ExploreYes. The Cica Serum is formulated for post-procedure calming. Apply after cleansing to comfort reactive skin. Avoid layering other actives for the first three to five days post-procedure.
Last reviewed by BIOSAR Scientific Team, PharmD, Cosmetic Chemistry, Pharmacy practice on .