Active ingredient

Calendula

INCICalendula Officinalis Flower Oil (and separately Calendula Officinalis Flower Extract)

Last reviewed by BIOSAR Scientific Team, PharmD, Cosmetic Chemistry, Pharmacy practice on April 28, 2026.

What it is

Calendula is a botanical extract from Calendula officinalis flowers, used in skincare to soothe inflamed, compromised, or post-procedure skin. Its triterpenoid faradiol esters and polysaccharides reduce erythema and support repair of the stratum corneum. Pairs broadly with most actives. No major conflicts.

Pregnancy and breastfeeding

Safe

Considered safe during pregnancy and breastfeeding.

Topical calendula is considered acceptable during pregnancy and lactation per Mother to Baby. Oral preparations are not recommended during pregnancy, but cosmetic surface use raises no documented concern.

Mechanism in detail

What Calendula does

Botanical with soothing properties, traditionally used on reactive skin. Delivered as oil and extract for complementary comfort and barrier support.

Evidence

What the research says

41% vs 63%Skin reactions during breast-cancer radiotherapyA phase III trial in 254 women receiving radiotherapy after breast-cancer surgery: moderate-to-severe skin reactions occurred in 41% with a calendula ointment and in 63% with trolamine.A clinical study in patients, in a medical setting. It is shown for the science of the ingredient, not as an example of cosmetic use.Read the study →J Clin Oncol 2004 (Pommier)

Where it helps