Morning routine
Not recommended in the morning. Always wear an SPF30+ during the day when using a Retinol routine.


Serenvit Retinol Serum is BIOSAR's evening renewal serum for the appearance of fine lines, uneven texture, and dullness. Encapsulated Retinol releases gradually overnight to support visible cell turnover; Squalane and Panthenol soothe the surface so the routine remains tolerable; Vitamin E supports antioxidant defense. Use it as the start of a Retinol routine — twice a week the first month, three times a week the second, then every night as tolerated. Always pair with a daily SPF50+ in the morning. Not recommended during pregnancy or breastfeeding. Pairs with the Serenvit Hyaluronic Acid Serum.
The gold-standard renewer, made kind to skin. BIOSAR's Vitalize Retinol resurfaces and refines fine lines and uneven texture while Squalane, Macadamia and Jojoba oils, Panthenol, Vitamin E and Pentavitin cushion and hydrate on a soothing Aloe Vera base. Skin looks smoother, firmer and visibly renewed. (Retinol formula — not for use during pregnancy or breastfeeding.)
Proven Benefits
Encapsulated Retinol reduces the look of fine lines overnight.
Gradual release supports visible cell turnover and smoother skin.
Squalane and Panthenol soothe the surface so renewal stays tolerable.
How the actives work together
Retinol renews the look of texture, fine lines and tone as skin turns over toward a smoother, more even finish. Because it is a demanding active, it is comprehensively buffered in the same drop: Squalane, Macadamia and Jojoba oils soften delivery, Panthenol calms, and Vitamin E steadies the surface. Pentavitin locks in moisture and the Aloe Vera base keeps it all tolerable, so serious renewal stays a comfortable nightly step.
Ingredient Research
In a year-long double-blind, vehicle-controlled trial, 0.1% stabilized retinol reduced crow's-feet fine lines by 44% by week 52. Benefits kept building at every checkpoint, backed by increased type I procollagen in the skin.
J Drugs Dermatol 2015 (Randhawa) — View research →In a 3-month trial, 96% of young participants using a panthenol-containing emollient stayed flare-free, versus 77% on reference care. Provitamin B5 keeps sensitive, barrier-stressed skin soothed and steady day after day.
J Dermatolog Treat 2017 — View research →Transparency
Application Guide
Not recommended in the morning. Always wear an SPF30+ during the day when using a Retinol routine.
Apply a few drops to clean dry skin before moisturizer. Start with twice a week and build up gradually.
Realistic Expectations
Skin drinks in the serum and feels comfortable, hydrated and cared for.
The targeted concern — hydration, tone, texture or firmness — starts to visibly improve.
Complete Care
Complete the routine
Retinol is photosensitizing — it breaks down under UV and can increase sun sensitivity. Night application paired with daily SPF50+ in the morning is the standard protocol.
Last reviewed by BIOSAR Scientific Team, PharmD, Cosmetic Chemistry, Pharmacy practice on .
Vitamin E supports antioxidant defense alongside the routine.
In a controlled trial, a squalane-and-shea moisturizer raised corneometer-measured skin hydration by 83.6% over two weeks. Squalane slots into the skin's own lipid layer to lock in moisture and restore a soft, comfortable barrier.
Results from published peer-reviewed studies on individual active ingredients. Individual product results may vary.
Retinol
Vitamin A derivative. BIOSAR formulates it as Vitalize Retinol — a stabilised grade that shields the fragile molecule from light and air and releases it into skin gradually, so it supports the renewal cycle and refines the look of fine lines and smoother texture over time while staying kinder to comfort. Used at night, with daytime sunscreen; not recommended during pregnancy or lactation.
Panthenol (Provitamin B5)
Provitamin B5 that supports the skin's repair and hydration signals. Widely used in sensitive, post-procedure, and daily-care formulas.
Squalane
Skin-mimicking lipid derived from plant sources. Delivers barrier support and a non-greasy finish. Pairs well with Retinol to improve tolerability.
Aloe Barbadensis Leaf Juice
Botanical humectant used as a comforting base across serums, baby care, and cleansers. High concentrations deliver noticeable cooling and hydration.
Tocopherol
It neutralizes free radicals at the lipid layer, helping limit oxidative damage to formula and skin surface.
Saccharide Isomerate
It binds to surface keratin and holds water in place, releasing only as the surface renews, for long-lasting moisture.
Macadamia Integrifolia Seed Oil
Oleic-rich lipids mirror skin's own emollients, spreading into a smooth conditioning layer that softens roughness.
Simmondsia Chinensis (Jojoba) Seed Oil
Its sebum-like esters condition the surface and help balance the look and feel of oily skin.
The serum's focused benefit reaches its peak with consistent daily use.
Individual results vary based on skin condition and routine consistency.