Morning routine
Not recommended in the morning. Always wear an SPF30+ during the day when using a Retinol routine.
I · FormulationFrom BIOSAR's Serenvit range
Retinol Serum
Serenvit Retinol Serum is BIOSAR's evening renewal serum for the appearance of fine lines, uneven texture, and dullness. Encapsulated Retinol releases gradually overnight to support visible cell turnover; Squalane and Panthenol soothe the surface so the routine remains tolerable; Vitamin E supports antioxidant defense. Use it as the start of a Retinol routine: twice a week the first month, three times a week the second, then every night as tolerated. Always pair with a daily SPF50+ in the morning. Not recommended during pregnancy or breastfeeding. Pairs with the Serenvit Hyaluronic Acid Serum.
- Retinol
- PanthenolPanthenol (Provitamin B5)
- Squalane
- Aloe VeraAloe Barbadensis Leaf Juice
If you are unsure it suits you, your dermatologist or pharmacist is the one to ask.
Dermatologically tested
Every BIOSAR product
SFDA
Registered
GMP · ISO 22716
Standard
Why it works
The gold-standard renewer, made kind to skin. BIOSAR's Vitalize Retinol resurfaces and refines fine lines and uneven texture while Squalane, Macadamia and Jojoba oils, Panthenol, Vitamin E and Pentavitin cushion and hydrate on a soothing Aloe Vera base. Skin looks smoother, firmer and visibly renewed. (Retinol formula — not for use during pregnancy or breastfeeding.)
- Retinol
- Panthenol
- Squalane
- Aloe Vera
- Vitamin E
- Pentavitin
Proven Benefits
What this product does for your skin
Reduced fine lines
Encapsulated Retinol reduces the look of fine lines overnight.
Renewed texture
Gradual release supports visible cell turnover and smoother skin.
Eased tolerance
Squalane and Panthenol soothe the surface so renewal stays tolerable.
Antioxidant support
Vitamin E supports antioxidant defense alongside the routine.
How this formula works
The renewal of retinol, delivered so gently your skin barely notices
Retinol renews the look of texture, fine lines and tone as skin turns over toward a smoother, more even finish. Because it is a demanding active, it is comprehensively buffered in the same drop: Squalane, Macadamia and Jojoba oils soften delivery, Panthenol calms, and Vitamin E steadies the surface. Pentavitin locks in moisture and the Aloe Vera base keeps it all tolerable, so serious renewal stays a comfortable nightly step.
Ingredient Research
Active ingredients backed by published studies
- −44%
Crow's-feet fine lines after one year, vehicle-controlled
A year-long double-blind, vehicle-controlled trial by the product's maker, in 62 people with photodamaged skin: stabilised retinol improved crow's-feet fine lines by 44%. Avoid retinoids during pregnancy and breastfeeding.
J Drugs Dermatol 2015 (Randhawa) — View research - 7 days
Better hydration and less water loss than the vehicle
A double-blind, placebo-controlled study in adult volunteers: after 7 days, skin treated with dexpanthenol was better hydrated and lost less water than skin treated with the vehicle alone. The abstract reports no effect sizes.
Arzneimittelforschung 2000 (Gehring & Gloor) — View research - 2 weeks
Aloe extract raised skin water content vs its vehicle
In 20 women, creams with freeze-dried aloe vera extract raised the water content of the outer skin layer on the forearm versus the same cream without it, after two weeks of daily use. Water loss through the skin did not change.
Dal'Belo SE, Gaspar LR, Maia Campos PMBG. Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques. Skin Res Technol. 2006;12(4):241-246. — View research
Published studies on ingredients, some tested inside other formulas. They are not tests of this product, and results vary from person to person.
Transparency
What's inside — and what's not
- 01
Retinol
Vitamin A derivative. BIOSAR formulates it as Vitalize Retinol — a stabilised grade that shields the fragile molecule from light and air and releases it into skin gradually, so it supports the renewal cycle and refines the look of fine lines and smoother texture over time while staying kinder to comfort. Used at night, with daytime sunscreen; not recommended during pregnancy or lactation.
- 02
Panthenol
Panthenol (Provitamin B5)
Provitamin B5 that supports the skin's repair and hydration signals. Widely used in sensitive, post-procedure, and daily-care formulas.
- 03
Squalane
Skin-mimicking lipid derived from plant sources. Delivers barrier support and a non-greasy finish. Pairs well with Retinol to improve tolerability.
- 04
Aloe Vera
Aloe Barbadensis Leaf Juice
Botanical humectant used as a comforting base across serums, baby care, and cleansers. High concentrations deliver noticeable cooling and hydration.
- 05
Vitamin E
Tocopherol
It neutralizes free radicals at the lipid layer, helping limit oxidative damage to formula and skin surface.
- 06
Pentavitin
Saccharide Isomerate
It binds to surface keratin and holds water in place, releasing only as the surface renews, for long-lasting moisture.
- 07
Macadamia Oil
Macadamia Integrifolia Seed Oil
Oleic-rich lipids mirror skin's own emollients, spreading into a smooth conditioning layer that softens roughness.
- 08
Jojoba Oil
Simmondsia Chinensis (Jojoba) Seed Oil
Its sebum-like esters condition the surface and help balance the look and feel of oily skin.
Application Guide
How to use
Evening routine
Apply a few drops to clean dry skin before moisturizer. Start with twice a week and build up gradually.
Realistic Expectations
What to expect
I
From day one
Felt on first use
Skin drinks in the serum and feels comfortable, hydrated and cared for.
II
Week 1–2
First visible results
The targeted concern — hydration, tone, texture or firmness — starts to visibly improve.
III
Week 4–6
Full targeted result
The serum's focused benefit reaches its peak with consistent daily use.
Individual results vary based on skin condition and routine consistency.
Complete the routine
Pairs beautifully with
Hydraderm Face Gel
Serenvit serums work harder on a hydrated canvas. Follow every serum with Hydraderm as your moisturizer step to seal each active in.
ExploreSunprotex SPF50+
Actives brighten and renew — SPF guards the result. Finish every morning routine with Sunprotex to keep your progress visible.
Explore
Frequently asked questions
Why do I need to use the Retinol Serum only at night?
Retinol is photosensitizing — it breaks down under UV and can increase sun sensitivity. Night application paired with daily SPF50+ in the morning is the standard protocol. Avoid retinoids during pregnancy and breastfeeding.
Last reviewed by BIOSAR Scientific Team, PharmD, Cosmetic Chemistry, Pharmacy practice on .
Claims & methodology
- Reduces the appearance of fine lines and uneven texture — Consumer perception study. Study on file at BIOSAR Laboratories.
Published references
- J Drugs Dermatol 2015 (Randhawa). pubmed.ncbi.nlm.nih.gov/25738849/
- Arzneimittelforschung 2000 (Gehring & Gloor). pubmed.ncbi.nlm.nih.gov/10965426/
- Dal'Belo SE, Gaspar LR, Maia Campos PMBG. Moisturizing effect of cosmetic formulations containing Aloe vera extract in different concentrations assessed by skin bioengineering techniques. Skin Res Technol. 2006;12(4):241-246.. pubmed.ncbi.nlm.nih.gov/17026654/