Active ingredient

Procapil

INCIBiotinoyl Tripeptide-1 + Apigenin + Oleanolic Acid (delivered in Butylene Glycol and PPG-26-Buteth-26)

Last reviewed by BIOSAR Scientific Team, PharmD, Cosmetic Chemistry, Pharmacy practice on April 28, 2026.

What it is

Procapil is a tri-active hair-care complex of biotinoyl tripeptide-1, apigenin, and oleanolic acid used in scalp care to support follicle anchoring and reduce hair shedding. It targets the dermal papilla, modulates 5-alpha-reductase activity, and improves microcirculation around the follicle. Pairs well with caffeine and copper-peptide scalp formulas. No major conflicts.

Pregnancy and breastfeeding

Safe

Considered safe during pregnancy and breastfeeding.

Procapil is a cosmetic-grade peptide-flavonoid complex with negligible systemic absorption from topical scalp use. Mother to Baby flags no concern for cosmetic peptide complexes during pregnancy or lactation.

Mechanism in detail

What Procapil does

Peptide-based complex for the hair follicle cycle. Supports the appearance of fuller, stronger-looking hair over a three-to-four-month course, in line with the natural hair-growth cycle.

Evidence

What the research says

67%Growing-to-resting hair ratio improved in 67% of usersPlacebo-controlled pilot, 35 men with over 20% of hairs in the resting phase: after 4 months, the growing-to-resting ratio improved significantly in 67% of the 18 on Procapil. Maker's data via a 2025 review; placebo result not given.Read the study →Int J Trichology 2025 (Bikash, review)
+31.6%Hair growth rate up 31.6% in 60 days, four-active serumIn 32 healthy adults with hair fall, a daily scalp serum with Procapil and three other actives raised measured hair growth rate by 10.5% at day 30 and 31.6% at day 60; thickness and density rose too. No control group; by the serum's brand.Read the study →J Cosmet Dermatol 2024 (Merja et al.)

Where it helps